preg_replace in update statement

[Hank]

I have a simple problem:

I have a varchar field in the database, and I want to remove all text
between WordA and WordB, including WordA and WordB, leaving all text
before WordA and after WordB intact.

Possible with just SQL?  I know I can write a PHP program to do it,
but it's not that important to spend that much time on.  I'd like one
SQL statement to do it.

Thanks!

-Hank