Better that `NOT IN`

[Junior Ortis]

Hi guys i have a problem, 3 big tables: item_instance about 15KK rows,
character_inventory 15KK rows, guild_bank_item 2KK rows.

And i need i clean on item_instance how this query:

DELETE FROM `item_instance` WHERE guid NOT IN(SELECT item FROM
`character_inventory`) AND guid NOT IN(SELECT item_guid FROM
`guild_bank_item`) AND
guid NOT IN(SELECT item_guid FROM `mail_items`) and guid NOT IN(SELECT
itemguid FROM `auctionhouse`);

Well atm is running about 13 hours, State = Sending Data.

I will be a better option ?

Thanks all !